Actithera appoints Steven Kelly as CEO and strengthens Board with Briggs Morrison as Chair and John Crowley as Independent Director. Learn More

Harnessing the Power of Chemistry in the Fight Against Cancer

Building the next generation Radioligand Therapy (RLT) platform
Actithera logo.
At Actithera we develop innovative radiotherapeutics by linking radioactive isotopes to carefully designed molecules. Our approach ensures rapid, specific, and sustained delivery of radiation to tumors, minimizing exposure to healthy tissues. We are a discovery company with an asset in IND enabling studies.

Our molecular design approaches result in Best-In-Class compounds, some of which are currently being prepared for clinical trials in cancer patients.

Radioligand therapy is truly personalized —patients are imaged first, and only those with sufficient tracer uptake receive the appropriate level of treatment.

RLT is generally better tolerated than traditional cancer treatments, and at Actithera, we raise the bar even further by designing molecules that concentrate more in tumors while sparing healthy tissues.

Our goal is to treat patients with fewer cycles

Our proprietary chemistry enables us to match the half-life of long-lived radionuclides with the residence time of our compounds in tumors. This alignment allows for effective treatment with fewer therapy cycles—reducing cumulative toxicity and minimizing unnecessary hospital visits, ultimately enhancing patients’ quality of life.

Actithera’s RLTs achieve prolonged tumor retention while maintaining excellent safety in preclinical models.

Actithera ligands

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Once an RLT is injected, it starts to distribute across the body.

Tumor

Radioactivity remains only in tumor

Radioactivity persists in tumor

RECENT NEWS/PRESS

Actithera significantly strengthens leadership team and Board as Company advances towards clinical development